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Impact of Activities of Daily Living (ADL) on PCI and Acute/Long-Term Mortality in Patients with AMI: Yamagata AMI Registry

[2022/10/5] According to Yamagata AMI registry, a lower level of activities of daily living (ADL) prior to presentation was associated with lower rates of PCI and higher mortality rates in patients with AMI, especially in the elderly, reported by Dr.Taku Toshima and colleagues, at Ishinomaki Red-Cross Hospital, in the October 1 issue of the Journal of Cardiology.

Dr.Toshima and colleagues studied 1,479 AMI patients enrolled in the Yamagata AMI Registry from 2015 to 2017, divided into three groups: those with preserved ADL prior to presentation, those with mild ADL decline, and those with severe ADL decline, to determine the impact of pre-presentation ADL on PCI and acute/long-term mortality.

Patients with reduced ADLs were older, more likely to be female, more likely to not undergo PCI, and had higher acute mortality rates compared to patients with preserved ADLs, and the proportion of patients with reduced ADLs increased with age.

Multivariate regression analysis showed that after adjusting for confounders, non-PCI and pre-present ADL decline were independent risk factors for acute mortality in AMI patients, and univariate and multivariate analyses further showed that ADL decline was associated with PCI. Cox proportional hazards analysis revealed that ADL decline is an independent risk factor for long-term mortality in patients with AMI.

Dr.Toshima and colleagues summarize, "Reduced ADL prior to presentation was associated with lower rates of PCI and higher mortality rates, especially in older AMI patients."

Toshima T, et al. J Cardiol. 2022; 80: 313-318

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