［2022/10/13] In Japanese patients with AMI treated with primary PCI, LVEF ≦35% at discharge was an independent predictor of sudden cardiac death, although the risk of sudden cardiac death after discharge was low, Dr.Kenji Hanada, Hirosaki University Graduate School of Medicine, and colleagues reported in the October issue of Circulation Journal.
Impact of LVEF Decline on Early Postdischarge Sudden Cardiac Death in Japanese Patients with AMI
Dr.Hanada et al. examined the impact of a decrease in LVEF on post-discharge sudden cardiac death in 1,429 patients (LVEF ≦35%: 199; LVEF >35%: n=1,230) who underwent primary PCI within 12 hours of AMI and were discharged alive at Hirosaki University Hospital between April 2005 and March 2019, with an average follow-up of 2.6 years. The impact of lower LVEF on sudden cardiac death after discharge was examined.
Kaplan-Meier survival curves showed that LVEF ≦35% was associated with all-cause mortality and sudden cardiac death, with sudden cardiac death occurring in 2.6% of patients with LVEF ≦35% at 1 year and 3.1% at 3 years, compared with 0.1% and 0.3%, respectively, for patients with >35% LVEF. 67% of sudden cardiac deaths in patients with LVEF ≦35% occurred within 4 months of discharge, and the frequency of sudden cardiac death decreased after this period. Cox proportional hazards models showed that LVEF ≦35% was an independent predictor of all-cause mortality and sudden cardiac death.
Dr.Hanada and colleagues concluded, "The incidence of sudden cardiac death in Japanese patients with AMI treated with primary PCI was relatively low, even in patients with LVEF ≦35% at discharge," .
Hanada K, Circ J. 2022; 86: 1490-1498
※コンテンツには、国内で未承認、適応外の医療機器、医薬品、または効能・効果/用法・用量の情報を含む場合がありますが、未承認、適応外の使用を推奨するものではありません。
ご注意 当サイト内の全ての記事と動画の転載・転送はご遠慮ください。なお、法律上保護されたコンテンツの無許可の転載、複製、転用等は、当該コンテンツの権利者等から損害賠償請求その他の法的手続を申し立てられ、事案によっては処罰される可能性、また、故意にそれらを受け取った場合も同様の措置を受ける可能性がございます。ご不明な点がございましたら当社までご連絡ください。
おすすめ
